Varaico: Literature-Extracted Genetic Variants

Gene:CYCS
Variant:p.A51V
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CYCS

NM_018947.6:p.A51V

Associated Papers

Physical and functional effects of substituting coevolved residues from Ω-loop C of yeast Iso-1-cytochrome c into human cytochrome c.

Frederick AK et al.

Journal of Inorganic Biochemistry, 2025

Phosphorylation of cytochrome c at tyrosine 48 finely regulates its binding to the histone chaperone SET/TAF-Iβ in the nucleus.

Tamargo-Azpilicueta J et al.

Protein Science : a Publication of the Protein Society, 2024

Human cytochrome C natural variants: Studying the membrane binding properties of G41S and Y48H by fluorescence energy transfer and molecular dynamics.

Muroni A et al.

International Journal of Biological Macromolecules, 2024

The Y49H cytochrome c variant enhances megakaryocytic maturation of K-562 cells.

Shafaei Pishabad Z et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2024

Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation.

Chin TC et al.

Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry, 2024

Effects of naturally occurring S47F/A mutations on the structure and function of human cytochrome c.

Li YY et al.

Journal of Inorganic Biochemistry, 2023

Structural Dynamics of the Precatalytic State of Human Cytochrome c upon T28C, G34C, and A50C Mutations: A Molecular Dynamics Simulation Perspective.

Nutho B et al.

Acs Omega, 2023

The oxidative nuclease activity of human cytochrome c with mutations in Ω-loop C/D.

Feng Y et al.

Biochimica Et Biophysica Acta. Proteins and Proteomics, 2023

Naturally Occurring I81N Mutation in Human Cytochrome c Regulates Both Inherent Peroxidase Activity and Interactions with Neuroglobin.

Feng Y et al.

Acs Omega, 2022

Influence of cysteine-directed mutations at the Ω-loops on peroxidase activity of human cytochrome c.

Samsri S et al.

Archives of Biochemistry and Biophysics, 2021

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity.

Fellner M et al.

The Biochemical Journal, 2021

A Novel Heterozygous Pathogenic Variation in CYCS Gene Cause Autosomal Dominant Non-Syndromic Thrombocytopenia 4 in a Large Chinese Family.

Che F et al.

Frontiers in Genetics, 2021

The importance of Asn52 in the structure-function relationship of human cytochrome c.

Lou D et al.

Rsc Advances, 2020

Comparison of the structural dynamic and mitochondrial electron-transfer properties of the proapoptotic human cytochrome c variants, G41S, Y48H and A51V.

Deacon OM et al.

Journal of Inorganic Biochemistry, 2020

Naturally Occurring A51V Variant of Human Cytochrome c Destabilizes the Native State and Enhances Peroxidase Activity.

Lei H et al.

The Journal of Physical Chemistry. B, 2019

Effect of V83G and I81A Substitutions to Human Cytochrome c on Acid Unfolding and Peroxidase Activity below a Neutral pH.

Lei H et al.

Biochemistry, 2019

Heightened Dynamics of the Oxidized Y48H Variant of Human Cytochrome c Increases Its Peroxidatic Activity.

Deacon OM et al.

Biochemistry, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."