Associated Papers
Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design.
Brixius-Anderko S et al.
The Journal of Biological Chemistry, 2019
Computational analysis of functional single nucleotide polymorphisms associated with the CYP11B2 gene.
Jia M et al.
Plos One, 2014
Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function.
Holloway CD et al.
Clinical Endocrinology, 2009
A novel CYP11B2 gene mutation in an Asian family with aldosterone synthase deficiency.
Løvås K et al.
The Journal of Clinical Endocrinology and Metabolism, 2009
Cosegregation of a novel homozygous CYP11B1 mutation with the phenotype of non-classical congenital adrenal hyperplasia in a consanguineous family.
Peters CJ et al.
Hormone Research, 2007
Inhibition of aldosterone biosynthesis by staurosporine.
Bureik M et al.
Biological Chemistry, 2005
[11beta-hydroxylase deficiency].
Mello MP et al.
Arquivos Brasileiros De Endocrinologia E Metabologia, 2004
Neonatal salt-wasting and 11 beta-hydroxylase deficiency in a child carrying a homozygous deletion hybrid CYP11B2 (aldosterone synthase)-CYP11B1 (11 beta-hydroxylase).
Ezquieta B et al.
Clinical Genetics, 2004
The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme.
Bechtel S et al.
European Journal of Biochemistry, 2002
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
Mulatero P et al.
European Journal of Endocrinology, 2001
Amino acid residue 147 of human aldosterone synthase and 11beta-hydroxylase plays a key role in 11beta-hydroxylation.
Fisher A et al.
The Journal of Clinical Endocrinology and Metabolism, 2000
Structure-function relationships of aldosterone synthase and 11 beta-hydroxylase enzymes: implications for human hypertension.
Fisher A et al.
Clinical and Experimental Pharmacology & Physiology. Supplement, 1998
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