Varaico: Literature-Extracted Genetic Variants

Gene:CYP11B2
Variant:p.P115L
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CYP11B2

NM_000498.3:p.P115L

Associated Papers

Association between CYP11B2 rs1799998 genetic variant with essential hypertension and antihypertensive response.

Abdelrazaq D et al.

Personalized Medicine, 2025

Correlation Between Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism and the Co-Occurrence of Left Ventricular Hypertrophy in Patients with Hypertension.

Li X et al.

International Heart Journal, 2025

Impact of Renin-Angiotensin-Aldosterone System (RAAS) Gene Polymorphism in Essential Hypertension and Antihypertensive Drug Therapy: A Review.

Adhikari A et al.

International Journal of Hypertension, 2025

Association of combined -344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population.

Nouhi Y et al.

Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne, 2024

Interplay between polygenic variants related immune response and lifestyle factors mitigate the chances of stroke in a genome-wide association study.

Park S

The British Journal of Nutrition, 2024

Association of the Single Nucleotide Polymorphisms in the Renin-Angiotensin-Aldosterone System with Hypertension in the Uzbek Population.

Zakirova D et al.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir, 2024

Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations.

Kalideen K et al.

Journal of Personalized Medicine, 2024

The prevalence and linkage disequilibrium of 21 genetic variations related to thrombophilia, folate cycle, and hypertension in reproductive age women of Rostov region (Russia).

Bordaeva OY et al.

Annals of Human Genetics, 2024

Alpha-adducin 1 (rs4961) gene and its expression associated with sodium sensitivity in hypertensive patients: a cohort study in the western Ukrainian population.

Sydorchuk L et al.

Endocrine Regulations, 2024

Genetic polymorphism of the CYP11B2 gene in an Iraqi patient with essential hypertension.

Mahdy IM et al.

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2024

Pertinence between risk of preeclampsia and the renin-angiotensin-aldosterone system (RAAS) gene polymorphisms: an updated meta-analysis based on 73 studies.

Wang X et al.

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 2023

Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan.

Shah WA et al.

Genes, 2023

Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population.

Shi M et al.

Journal of the American Heart Association, 2022

36193932 (PubMed )
Supplement: JAH3-11-e025245-s001.pdf

Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the essential arterial hypertension.

Sydorchuk AR et al.

Endocrine Regulations, 2022

Contribution of the ACE (rs1799752) and CYP11B2 (rs1799998) Gene Polymorphisms to Atrial Fibrillation in the Tunisian Population.

Gouissem I et al.

Biological Research for Nursing, 2022

Aldosterone synthase (CYP11B2) deficiency among Palestinian infants: Three novel variants and genetic heterogeneity.

Faingelernt Y et al.

American Journal of Medical Genetics. Part A, 2021

Relationship between SCN5A gene H558R polymorphism and atrial fibrillation in Tibetan and Han nationalities at high altitude.

Liu J et al.

Medicine, 2021

Angiotensin-Converting Enzyme Gene Polymorphism Influences Gastrointestinal Motility in Type 2 Diabetes Mellitus.

Malik A et al.

Biochemical Genetics, 2021

Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.

Wang L et al.

The Journal of International Medical Research, 2020

Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.

Mopidevi B et al.

The Journal of Biological Chemistry, 2020

Lack of association between CYP11B2 -344T/C polymorphism and transient ischemic attack in a Chinese population.

Fan J et al.

The Journal of International Medical Research, 2020

Pharmacogenomics of Hypertension Treatment.

Rysz J et al.

International Journal of Molecular Sciences, 2020

The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.

Sydorchuk L et al.

Endocrine Regulations, 2020

Association of CYP11B2 gene polymorphism with preeclampsia in north east of Iran (Khorasan province).

Azimi-Nezhad M et al.

Gene, 2020

Renin-angiotensin system gene variants and risk of early- and late-onset preeclampsia: A single center case-control study.

Procopciuc LM et al.

Pregnancy Hypertension, 2019

Association of polymorphisms of CYP11B2 gene -344C/T and ACE gene I/D with antihypertensive response to angiotensin receptor blockers in Chinese with hypertension.

Gong H et al.

Journal of Genetics, 2019

Association of aldosterone synthase CYP11B2 (-344C/T) gene polymorphism with essential hypertension and left ventricular hypertrophy in the Egyptian population.

Abdel Ghafar MT

Clinical and Experimental Hypertension (new York, N.y. : 1993), 2019

The Associations of PMF1, ICAM1, AGT, TRIM65, FBF1, and ACOX1 Variants With Leukoaraiosis in Chinese Population.

Huang WQ et al.

Frontiers in Genetics, 2019

31396257 (PubMed )
Supplement: Table_1.xlsx › 28_SNPs

Modulation of aldosterone levels by aldosterone synthase promoter polymorphism and association with eGFR decline in patients with chronic kidney disease.

Qian J et al.

Discovery Medicine, 2018

[Genetic Polymorphisms Associated with the Onset of Arterial Hypertension in a Portuguese Population].

Sousa AC et al.

Acta Medica Portuguesa, 2018

Association between A1166C Polymorphism of the Angiotensin II Type-1 Receptor Gene and Type-2 Diabetic Nephropathy in an Indonesian Malay Population.

Ali Z et al.

Acta Medica Indonesiana, 2018

Association of gene polymorphisms of aldosterone synthase and angiotensin converting enzyme in pre-eclamptic South African Black women.

Aung M et al.

Pregnancy Hypertension, 2018

A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension.

Zhang H et al.

Medicine, 2017

The impacts of the interaction of genetic variation, CYP11β2 and NEDD4L, with sodium intake on pediatric obesity with gender difference: a 3-year panel study.

Lee M et al.

International Journal of Obesity (2005), 2017

Prognostic Value of Different Allelic Polymorphism of Aldosterone Synthase Receptor in a Congestive Heart Failure European Continental Ancestry Population.

Feola M et al.

Archives of Medical Research, 2017

Association of the -344T/C polymorphism in aldosterone synthase gene promoter with left ventricular structure in Chinese Han: A meta-analysis.

Yin C et al.

Clinical and Experimental Hypertension (new York, N.y. : 1993), 2017

Association between selected gene polymorphisms and statin metabolism, risk of ischemic stroke and cardiovascular disorders.

Kotlęga D et al.

Postepy Higieny I Medycyny Doswiadczalnej (online), 2016

Association of Mineralocorticoid Receptor Polymorphism I180V With Left Ventricular Hypertrophy in Resistant Hypertension.

Ritter AM et al.

American Journal of Hypertension, 2016

Clinical implications of nonsarcomeric gene polymorphisms in hypertrophic cardiomyopathy.

García-Honrubia A et al.

European Journal of Clinical Investigation, 2016

Analysis of the gene polymorphism of aldosterone synthase (CYP11B2) and atrial natriuretic peptide (ANP) in women with preeclampsia.

Bogacz A et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2016

Polymorphisms of three genes (ACE, AGT and CYP11B2) in the renin-angiotensin-aldosterone system are not associated with blood pressure salt sensitivity: A systematic meta-analysis.

Sun J et al.

Blood Pressure, 2016

Association of echocardiographic left ventricular structure and -344C/T aldosterone synthase gene variant: A meta-analysis.

Wang L et al.

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2015

Aldosterone Synthase Promoter Polymorphism and Cardiovascular Phenotypes in a Large, Multiethnic Population-Based Study.

Byrd JB et al.

Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research, 2015

Retracted: Association of aldosterone synthase (CYP11B2) gene polymorphism with IgA nephropathy risk and progression of IgA nephropathy.

Zhong W et al.

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2015

The CYP11B2 -344C/T variant is associated with ischemic stroke risk: An updated meta-analysis.

Yu Y

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2015

Refractory hyperaldosteronism in heart failure is associated with plasma renin activity and angiotensinogen polymorphism.

Vergaro G et al.

Journal of Cardiovascular Medicine (hagerstown, Md.), 2015

Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease.

Yilmaz M et al.

Iranian Journal of Kidney Diseases, 2015

Relationship between CYP11B2-344T>C polymorphsim and atrial fibrillation: A meta-analysis.

Fu X et al.

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2015

Variable transcriptional regulation of the human aldosterone synthase gene causes salt-dependent high blood pressure in transgenic mice.

Mopidevi B et al.

Circulation. Cardiovascular Genetics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."