Varaico: Literature-Extracted Genetic Variants

Gene:CYP1A1
Variant:p.I462V
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CYP1A1

NM_001319217.2:p.I462V

Associated Papers

Meta-Analysis of CYP1A1 MspI and Ile462Val Polymorphisms in Cancer Susceptibility Among Different Ethnic Populations.

Yousuf A et al.

Environmental and Molecular Mutagenesis, 2025

Decoding the Impact of Genetic Polymorphisms in Xenobiotic Metabolizing Enzymes and Ovarian Cancer: A Comprehensive Review.

Sistla HC et al.

Environmental and Molecular Mutagenesis, 2025

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by BRCA1 mutation.

Liu J et al.

Science Advances, 2025

40712032 (PubMed )
Supplement: sciadv.adi2370_tables_s8_and_s9.zip › adi2370_table_s9.xlsx › BRCA1-mutant_corrected_iPSC

A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC.

Wang Z et al.

Cellular & Molecular Biology Letters, 2025

Impact of single nucleotide variants in estrogen genes on ovarian cancer risk: a systematic review and meta-analysis.

Aguiar MP et al.

Endocrine Oncology (bristol, England), 2025

The association of combined GSTM1, GSTT1, and GSTP1 genetic polymorphisms with lung cancer risk in male Iraqi Waterpipe Tobacco (Nargila) smokers.

Kudhair BK et al.

Cancer Epidemiology, 2024

Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms: A Review.

Mokhosoev IM et al.

Cells, 2024

Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations.

Gupta M et al.

Eye (london, England), 2024

Influence of Genetic Polymorphisms on the Age at Cancer Diagnosis in a Homogenous Lynch Syndrome Cohort of Individuals Carrying the MLH1:c.1528C>T South African Founder Variant.

Ndou L et al.

Biomedicines, 2024

39457514 (PubMed )
Supplement: biomedicines-12-02201-s001.zip › Supplementary_Table_S1.pdf

Low-Penetrance Susceptibility Variants in Colorectal Cancer-Current Outlook in the Field.

Szuman M et al.

International Journal of Molecular Sciences, 2024

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility.

Xiao Y et al.

Archives of Toxicology, 2024

Gene variants polymorphisms and uterine leiomyoma: an updated review.

Upadhyay S et al.

Frontiers in Genetics, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.

Huang YC et al.

Journal of Personalized Medicine, 2023

37763159 (PubMed )
Supplement: jpm-13-01392-s001.zip › Supplementary_Table_S3.xlsx › Variants

Assessment of the association of CYP1A1 gene polymorphisms with the susceptibility of cervical cancer: A case-control study and meta-analysis.

Barek MA et al.

Heliyon, 2023

37483787 (PubMed )
Supplement: mmc2.docx

Association of Interactions between Metabolic 'Caretaker' Genes, p53, MDM2, and Tobacco Use with the Risk of Oral Cancer: A Multifactor Dimensionality Reduction Approach.

Singh RD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

Genic-intergenic polymorphisms of CYP1A genes and their clinical impact.

Kukal S et al.

Gene, 2023

Meta-Analysis of 49 SNPs Covering 25,446 Cases and 41,106 Controls Identifies Polymorphisms in Hormone Regulation and DNA Repair Genes Associated with Increased Endometrial Cancer Risk.

Das AP et al.

Genes, 2023

36981012 (PubMed )
Supplement: genes-14-00741-s001.zip › Table_S1.xlsx › Table_S1

Strong Cumulative Evidence of Associations of 6 Single Nucleotide Polymorphisms with Ovarian Cancer Risk: An Umbrella Review.

Huo YJ et al.

Journal of Clinical Medicine, 2023

36902812 (PubMed )
Supplement: jcm-12-02025-s001.zip › jcm-2179460-supplementary › Supplementary_File_S2.pdf

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling.

Deserranno K et al.

Frontiers in Pharmacology, 2023

38026945 (PubMed )
Supplement: DataSheet1.ZIP › SupplementaryMaterials › SupplementaryMaterials_Tables_S4-S9.xlsx › NA19785_R10.4.1_AldyCalls

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors.

Maekawa K et al.

Drug Metabolism and Pharmacokinetics, 2022

The formation of SCEs as an effect of occupational exposure to formaldehyde.

Ghelli F et al.

Archives of Toxicology, 2022

Polymorphisms in PAH metabolising enzyme CYP1A1 in colorectal cancer and their clinicopathological correlations.

Cheng T et al.

Pathology, Research and Practice, 2022

Genetic variants affecting chemical mediated skin immunotoxicity.

Rodrigues de Souza I et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2022

Mutational Landscape Screening Through Comprehensive In Silico Analysis for Polycystic Ovarian Syndrome-Related Genes.

Dhar S et al.

Reproductive Sciences (thousand Oaks, Calif.), 2022

Polymorphisms of Cytochromes P450 and Glutathione S-Transferases Synergistically Modulate Risk for Parkinson's Disease.

Fan HH et al.

Frontiers in Aging Neuroscience, 2022

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Gene polymorphisms and risk of head and neck squamous cell carcinoma: a systematic review.

Rajabi-Moghaddam M et al.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2022

The Relationship of ABCB1/MDR1 and CYP1A1 Variants with the Risk of Disease Development and Shortening of Overall Survival in Patients with Multiple Myeloma.

Zmorzynski S et al.

Journal of Clinical Medicine, 2021

Independent and Interactive Effect of CYPs and GSTs Genetic Variants and Tobacco Smoking on the Risk of Non-Small Cell Lung Carcinoma.

Pathak AK et al.

Archives of Medical Research, 2021

Functional Analyses of Four CYP1A1 Missense Mutations Present in Patients with Atypical Femoral Fractures.

Ugartondo N et al.

International Journal of Molecular Sciences, 2021

Individual and combined effects of GSTM1, GSTT1, and GSTP1 polymorphisms on lung cancer risk: A meta-analysis and re-analysis of systematic meta-analyses.

Zhang WP et al.

Medicine, 2021

34190143 (PubMed )
Supplement: medi-100-e26104-s001.pdf

An Example of Personalized Treatment in HR+ HER2+ Long Survivor Breast Cancer Patient (Case Report).

Panebianco M et al.

Current Oncology (toronto, Ont.), 2021

34070464 (PubMed )
Supplement: curroncol-28-00184-s001.zip › curroncol-1167217-SI.pdf

The role of phase I, phase II, and DNA-repair gene polymorphisms in the damage induced by formaldehyde in pathologists.

Ghelli F et al.

Scientific Reports, 2021

Sequence Polymorphism in Xenobiotic Metabolising Genes in Iraqi Colorectal Cancer Patients.

Ibrahem SQ et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2021

Discovery of breast cancer risk genes and establishment of a prediction model based on estrogen metabolism regulation.

Zhao F et al.

Bmc Cancer, 2021

Drug-Drug Interactions and Pharmacogenomic Evaluation in Colorectal Cancer Patients: The New Drug-PIN® System Comprehensive Approach.

Roberto M et al.

Pharmaceuticals (basel, Switzerland), 2021

33467633 (PubMed )
Supplement: pharmaceuticals-14-00067-s001.pdf

Risk of Colorectal Carcinoma May Predispose to the Genetic Variants of the GST, CYP450, and TP53 Genes Among Nonsmokers in the Saudi Community.

Sindi IA et al.

International Journal of General Medicine, 2021

Genetic Variations in Cytochrome P450 1A1 and 1B1 Genes in a Cohort of Patients from Iraq Diagnosed with Breast Cancer.

Ibrahem SQ et al.

Breast Cancer : Basic and Clinical Research, 2021

Current and New Biomarkers for Early Detection, Prognostic Stratification, and Management of Gallbladder Cancer Patients.

García P et al.

Cancers, 2020

Genotype of Null Polymorphisms in Genes GSTM1, GSTT1, CYP1A1, and CYP1A1*2A (rs4646903 T>C)/CYP1A1*2C (rs1048943 A>G) in Patients with Larynx Cancer in Southeast Spain.

Sánchez-Siles M et al.

Cancers, 2020

Environmental exposures and breast cancer risk in the context of underlying susceptibility: A systematic review of the epidemiological literature.

Zeinomar N et al.

Environmental Research, 2020

The correlation of combined OGG1, CYP1A1 and GSTP1 gene variants and risk of lung cancer of male Iraqi waterpipe tobacco smokers.

Kudhair BK et al.

Molecular Biology Reports, 2020

CYP1A1 gene (6235T<C) polymorphism as a risk factor for polycystic ovarian syndrome among Egyptian women.

Bayoumy N et al.

Human Fertility (cambridge, England), 2020

Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.

Li G et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."