Varaico: Literature-Extracted Genetic Variants

Gene:CYP1A1
Variant:p.G45D
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CYP1A1

NM_001319217.2:p.G45D

Associated Papers

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Multi-omic analyses of a twin pair with mirror image cleft lip identifies pathogenic variant in FGF20 modified by differential methylation upstream of ZFP57.

Awotoye W et al.

Medrxiv : the Preprint Server for Health Sciences, 2024

Polycyclic aromatic hydrocarbon and its adducts in peripheral blood: Gene and environment interaction among Chinese population.

Guo L et al.

Environment International, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.

Chamboko CR et al.

International Journal of Molecular Sciences, 2023

36834793 (PubMed )
Supplement: ijms-24-03383-s001.zip › ijms-2130595-supplementary.pdf

Activated leukocyte cell adhesion molecule/cluster of differentiation 166 rs10933819 (G>A) variant is associated with familial intracranial aneurysms.

Aitkulova A et al.

Biomedical Reports, 2022

35815187 (PubMed )
Supplement: Supplementary_Data.xlsx › 713_shortlisted_variants

New insights of CYP1A in endogenous metabolism: a focus on single nucleotide polymorphisms and diseases.

Lu J et al.

Acta Pharmaceutica Sinica. B, 2020

CYP1A1, GSTM1 and GSTT1 genetic polymorphisms and gastric cancer risk among Japanese: A nested case-control study within a large-scale population-based prospective study.

Hidaka A et al.

International Journal of Cancer, 2016

Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder.

Medhasi S et al.

Neuropsychiatric Disease and Treatment, 2016

Characterization of the Gly45Asp variant of human cytochrome P450 1A1 using recombinant expression.

Lee SH et al.

Toxicology Letters, 2015

Interaction effect of serum 25-hydroxyvitamin D levels and CYP1A1, CYP1B1 polymorphisms on blood pressure in an elderly population.

Park HY et al.

Journal of Hypertension, 2015

Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: a case-control study.

Shen Y et al.

The Journal of Obstetrics and Gynaecology Research, 2014

A multicenter case-control study on screening of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in han chinese.

Shen Y et al.

Gynecologic and Obstetric Investigation, 2014

CYP1A1 genetic polymorphism and polycyclic aromatic hydrocarbons on pulmonary function in the elderly: haplotype-based approach for gene-environment interaction.

Choi YH et al.

Toxicology Letters, 2013

Genetic polymorphisms in metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine.

Kim D et al.

Journal of Applied Toxicology : Jat, 2013

Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy.

Preissner SC et al.

Plos One, 2013

24340040 (PubMed )
Supplement: pone.0082562.s002.xlsx › CYP_SNP

Functional analyses of endometriosis-related polymorphisms in the estrogen synthesis and metabolism-related genes.

Wang HS et al.

Plos One, 2012

Association of the G134A and G184C Polymorphisms in the CYP1A1 Gene with Lung Cancer Incidence.

Ryu DY et al.

Toxicological Research, 2008

The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers.

Chen B et al.

The Science of the Total Environment, 2007

Japanese single nucleotide polymorphism database for 267 possible drug-related genes.

Iida A et al.

Cancer Science, 2006

The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.

Ferraro TN et al.

Epilepsy & Behavior : E&b, 2005

Screening for deleterious nonsynonymous single-nucleotide polymorphisms in genes involved in steroid hormone metabolism and response.

Johnson MM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2005

Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.

Jiang Z et al.

Human Mutation, 2005

Genetic polymorphisms of CYP1A1 in a Korean population.

Park DW et al.

Archives of Toxicology, 2004

[SNP collection, pharmacogenomics, and the future of drug therapy].

Iida A et al.

Gan to Kagaku Ryoho. Cancer & Chemotherapy, 2002

906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.

Saito S et al.

Journal of Human Genetics, 2002

Relationship between single nucleotide polymorphisms in CYP1A1 and CYP1B1 genes and the bone mineral density and serum lipid profiles in postmenopausal Japanese women taking hormone therapy.

Quan J et al.

Menopause (new York, N.y.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."