Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
APF2: an improved ensemble method for pharmacogenomic variant effect prediction.
Zhou Y et al.
The Pharmacogenomics Journal, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.
Chamboko CR et al.
International Journal of Molecular Sciences, 2023
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.
Neyshaburinezhad N et al.
Journal of Personalized Medicine, 2021
In silico screening and analysis of nonsynonymous SNPs in human CYP1A2 to assess possible associations with pathogenicity and cancer susceptibility.
Navapour L et al.
Scientific Reports, 2021
Impact of peripheral mutations on the access channels of human cytochrome P450 1A2.
Ying B et al.
Journal of Biomolecular Structure & Dynamics, 2020
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Zhou Y et al.
The Pharmacogenomics Journal, 2019
Functional characterization of 20 allelic variants of CYP1A2.
Ito M et al.
Drug Metabolism and Pharmacokinetics, 2015
Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.
Palma BB et al.
The Pharmacogenomics Journal, 2010
Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.
Zhou SF et al.
Drug Metabolism Reviews, 2010
Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.
Zhou SF et al.
The Aaps Journal, 2009
Genetic polymorphism and variability of chemical carcinogenesis.
Belitsky GA et al.
Biochemistry. Biokhimiia, 2008
CYP1A2 F21L and F186L polymorphisms in an Italian population sample.
Pucci L et al.
Drug Metabolism and Pharmacokinetics, 2007
Functional analysis of three CYP1A2 variants found in a Japanese population.
Saito Y et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005
Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.
Murayama N et al.
The Journal of Pharmacology and Experimental Therapeutics, 2004
Genetic polymorphism of human cytochrome p450 involved in drug metabolism.
Nagata K et al.
Drug Metabolism and Pharmacokinetics, 2002
Identification of novel polymorphisms in the 5' flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance.
Aitchison KJ et al.
Pharmacogenetics, 2000
Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese.
Huang JD et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 1999