Associated Papers
Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.
Esteves F et al.
Biomolecules, 2023
Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding.
Esteves F et al.
International Journal of Molecular Sciences, 2020
Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase.
Udhane SS et al.
Frontiers in Pharmacology, 2017
Pharmacogenomics of human P450 oxidoreductase.
Pandey AV et al.
Frontiers in Pharmacology, 2014
Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism.
Flück CE et al.
Biochemical and Biophysical Research Communications, 2010
Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase.
Pandey AV et al.
Biochemical and Biophysical Research Communications, 2010
Restoration of mutant cytochrome P450 reductase activity by external flavin.
Nicolo C et al.
Molecular and Cellular Endocrinology, 2010
Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19.
Agrawal V et al.
Pharmacogenetics and Genomics, 2008
P450 oxidoreductase: genetic polymorphisms and implications for drug metabolism and toxicity.
Hart SN et al.
Expert Opinion on Drug Metabolism & Toxicology, 2008
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