Varaico: Literature-Extracted Genetic Variants

Gene:CYP1A2
Variant:p.L55M
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CYP1A2

NM_000761.5:p.L55M

Associated Papers

GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes.

Coulter AJ et al.

Clinical Pharmacology and Therapeutics, 2026

Influence of the CYP1A2 genotype on the exercise performance of physically active individuals under caffeine supplementation: a systematic review.

Messenburger GP et al.

Nutrition Research (new York, N.y.), 2025

Influence of genetic polymorphisms on gefitinib pharmacokinetics and adverse drug reactions in non-small cell lung cancer patients.

Shenoy PV et al.

Cancer Metastasis Reviews, 2025

41199076 (PubMed )
Supplement: 10555_2025_10299_MOESM1_ESM.xlsx › Gene_and_SNP_details

Pharmacogenetics and pharmacometabolomics predictors of clozapine and norclozapine pharmacokinetic exposure in healthy volunteers.

Albitar O et al.

European Journal of Clinical Pharmacology, 2025

Exploratory Study on Genetic Variants Related to Hydatidosis Susceptibility and Albendazole Pharmacogenetics in the Cusco Region in Peru.

Jaramillo-Valverde L et al.

Frontiers in Bioscience (scholar Edition), 2025

CYP1A2 expression and activity in a large panel of human nonneoplastic surgical liver samples: Influence of genetics, lifestyle, and other factors.

Kuhn UD et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Impact of single nucleotide variants in estrogen genes on ovarian cancer risk: a systematic review and meta-analysis.

Aguiar MP et al.

Endocrine Oncology (bristol, England), 2025

Case Report: I want more olanzapine: pharmacogenetic insights into a patient's preference for high-dose olanzapine.

Hudnik LK et al.

Frontiers in Psychiatry, 2025

Caffeine Consumption and Interaction with ADORA2A, CYP1A2 and NOS1 Variants Do Not Influence Age at Onset of Machado-Joseph Disease.

Martins AC et al.

Cerebellum (london, England), 2024

Challenging pharmacotherapy management of a psychotic disorder due to a delicate pharmacogenetic profile and drug-drug interactions: a case report and literature review.

Belančić A et al.

Croatian Medical Journal, 2024

Association between CYP1A2 gene variants -163 C/A (rs762551) and -3860 G/A (rs2069514) and bladder cancer susceptibility.

Iqbal MS et al.

Bmc Cancer, 2024

Exploring clozapine pharmacokinetics in Tunisian schizophrenic patients: A population-based modelling approach investigating the impact of genetic and non-genetic variables.

Mansour K et al.

Basic & Clinical Pharmacology & Toxicology, 2024

Habitual coffee consumption and risk of dementia in older persons: modulation by CYP1A2 polymorphism.

Lefèvre-Arbogast S et al.

European Journal of Epidemiology, 2024

CYP1A2*F Polymorphism Contributes at Least Partially to the Variability of Plasma Levels of Dehydroaripiprazole, an Active Metabolite of Aripiprazole, in Schizophrenic Patients.

Suzuki T et al.

Drug Metabolism and Bioanalysis Letters, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients.

Fekete F et al.

Scientific Reports, 2023

The Impact of the CYP2D6 and CYP1A2 Gene Polymorphisms on Response to Duloxetine in Patients with Major Depression.

Maciaszek J et al.

International Journal of Molecular Sciences, 2023

Genic-intergenic polymorphisms of CYP1A genes and their clinical impact.

Kukal S et al.

Gene, 2023

The Progress and Pitfalls of Pharmacogenetics-Based Precision Medicine in Schizophrenia Spectrum Disorders: A Systematic Review and Meta-Analysis.

Teng Y et al.

Journal of Personalized Medicine, 2023

36983653 (PubMed )
Supplement: jpm-13-00471-s001.zip › Supplementary_Table_S2.xlsx › Table_S2

Pharmacogenetics of anxiety and depression in Alzheimer's disease.

Cacabelos R et al.

Pharmacogenomics, 2023

Influence of CYP450 Enzymes and ABCB1 Polymorphisms on Clopidogrel Response in Moroccan Patients with Acute Coronary Syndromes.

Mouhrach I et al.

Pharmacogenomics and Personalized Medicine, 2023

Polymorphism of Drug Transporters, Rather Than Metabolizing Enzymes, Conditions the Pharmacokinetics of Rasagiline.

Zubiaur P et al.

Pharmaceutics, 2022

Contribution of CYP19A1, CYP1A1, and CYP1A2 polymorphisms in coronary heart disease risk among the Chinese Han population.

Ye W et al.

Functional & Integrative Genomics, 2022

Clinical implications of germline variations for treatment outcome and drug resistance for small molecule kinase inhibitors in patients with non-small cell lung cancer.

Heersche N et al.

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2022

CYP1A2 mRNA Expression Rather than Genetic Variants Indicate Hepatic CYP1A2 Activity.

Fekete F et al.

Pharmaceutics, 2022

Integration of liquid biopsy and pharmacogenomics for precision therapy of EGFR mutant and resistant lung cancers.

Kolesar J et al.

Molecular Cancer, 2022

CYP1A2 polymorphisms modify the association of habitual coffee consumption with appetite, macronutrient intake, and body mass index: results from an observational cohort and a cross-over randomized study.

Gkouskou KG et al.

International Journal of Obesity (2005), 2022

Pharmacogenetics of Praziquantel Metabolism: Evaluating the Cytochrome P450 Genes of Zimbabwean Patients During a Schistosomiasis Treatment.

Zdesenko G et al.

Frontiers in Genetics, 2022

35754834 (PubMed )
Supplement: DataSheet1.pdf

Profiling of warfarin pharmacokinetics-associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics-dosing algorithm.

Ndadza A et al.

Journal of Thrombosis and Haemostasis : Jth, 2021

Clinical and genetic influencing factors on clozapine pharmacokinetics in Tunisian schizophrenic patients.

Ammar H et al.

The Pharmacogenomics Journal, 2021

Functional Characterization of 21 Rare Allelic CYP1A2 Variants Identified in a Population of 4773 Japanese Individuals by Assessing Phenacetin O-Deethylation.

Kumondai M et al.

Journal of Personalized Medicine, 2021

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.

Yip VLM et al.

British Journal of Clinical Pharmacology, 2021

Organophosphate pesticide exposure, hormone levels, and interaction with PON1 polymorphisms in male adolescents.

Suárez B et al.

The Science of the Total Environment, 2021

Influence of Pathogenic and Metabolic Genes on the Pharmacogenetics of Mood Disorders in Alzheimer's Disease.

Cacabelos R et al.

Pharmaceuticals (basel, Switzerland), 2021

Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters.

Iannaccone T et al.

Pharmaceuticals (basel, Switzerland), 2021

CYP Genotypes Are Associated with Toxicity and Survival in Osteosarcoma Patients.

Trujillo-Paolillo A et al.

Journal of Adolescent and Young Adult Oncology, 2020

Variant Interpretation in Current Pharmacogenetic Testing.

Luvsantseren S et al.

Journal of Personalized Medicine, 2020

Associations between CYP2J2 (-76G>T) rs890293 polymorphism and age-related macular degeneration.

Liutkeviciene R et al.

Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020

CYP1A2 rs762551 and ADORA2A rs5760423 Polymorphisms in Patients with Blepharospasm.

Siokas V et al.

Journal of Molecular Neuroscience : Mn, 2020

Association of CYP19A1 and CYP1A2 genetic polymorphisms with type 2 diabetes mellitus risk in the Chinese Han population.

Yang Y et al.

Lipids in Health and Disease, 2020

Effects of CYP1A2 and ADORA2A Genotypes on the Ergogenic Response to Caffeine in Professional Handball Players.

Muñoz A et al.

Genes, 2020

Five genetic polymorphisms of cytochrome P450 enzymes in the Czech non-Roma and Czech Roma population samples.

Dlouhá L et al.

Drug Metabolism and Personalized Therapy, 2020

The plateau at V˙ O2max is associated with anaerobic alleles.

Keiller DR et al.

Journal of Science and Medicine in Sport, 2020

Impact of AhRR (565C > G) polymorphism on dioxin dependent CYP1A2 induction.

Chernyak YI et al.

Toxicology Letters, 2020

SNP's in xenobiotic metabolism and male infertility.

Hekim N et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Cigarette smoking and heavy coffee consumption affecting response to olanzapine: The role of genetic polymorphism.

Djordjevic N et al.

The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry, 2020

New insights of CYP1A in endogenous metabolism: a focus on single nucleotide polymorphisms and diseases.

Lu J et al.

Acta Pharmaceutica Sinica. B, 2020

Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine.

Chamnanphon M et al.

Pharmacogenomics and Personalized Medicine, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."