Associated Papers
Genetic variants of flavin-containing monooxygenase (FMO) 1 and FMO3 in 5887 dogs influenced oxygenations of probe substrates benzydamine, trimethylamine, and methyl p-tolyl sulfide.
Uno Y et al.
Biochemical Pharmacology, 2026
Genetic variants of cytochrome P450 2C21 identified by screening 6344 dogs influenced oxidations of the probe drug omeprazole.
Uno Y et al.
Biochemical Pharmacology, 2025
Genetic variants in dog cytochrome P450 2B6 and their relevance to interindividual variability of oxidations of probe drug propofol.
Uno Y et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025
PCR-based detection of hereditary mutations in SLC2A9, BTBD17, and NECAP1 among native Korean dog breeds.
Kang M et al.
Journal of Veterinary Science, 2025
Evaluation of the relationship between cytochrome P450 (CYP) 1A2 gene copy number variation and CYP1A2 protein content and enzyme activity in canine liver.
Zamora FG et al.
Frontiers in Veterinary Science, 2025
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.
Meadows JRS et al.
Genome Biology, 2023
A novel canine reference genome resolves genomic architecture and uncovers transcript complexity.
Wang C et al.
Communications Biology, 2021
Sequencing of the Canine Cytochrome P450 CYP2C41 Gene and Genotyping of Its Polymorphic Occurrence in 36 Dog Breeds.
Karakus E et al.
Frontiers in Veterinary Science, 2021
Genetic diversity of cytochrome P450 1A2 with different metabolic activities in domestic cats.
Sugiyama S et al.
The Journal of Veterinary Medical Science, 2019
Canine cytochrome P-450 pharmacogenetics.
Court MH
The Veterinary Clinics of North America. Small Animal Practice, 2013
Comparative and veterinary pharmacogenomics.
Mosher CM et al.
Handbook of Experimental Pharmacology, 2010
Characterization of substrate specificity of dog CYP1A2 using CYP1A2-deficient and wild-type dog liver microsomes.
Mise M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2008
Genetic polymorphism of cytochrome P450s in beagles: possible influence of CYP1A2 deficiency on toxicological evaluations.
Kamimura H
Archives of Toxicology, 2006
Identification of non-functional allelic variant of CYP1A2 in dogs.
Mise M et al.
Pharmacogenetics, 2004
Identification of the novel canine CYP1A2 1117 C > T SNP causing protein deletion.
Tenmizu D et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2004