Varaico: Literature-Extracted Genetic Variants

Gene:CYP1B1
Variant:p.L432V
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CYP1B1

NM_000104.4:p.L432V

Associated Papers

Decoding the Impact of Genetic Polymorphisms in Xenobiotic Metabolizing Enzymes and Ovarian Cancer: A Comprehensive Review.

Sistla HC et al.

Environmental and Molecular Mutagenesis, 2025

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Germline Non-CDKN2A Variants in Melanoma and Associated Hereditary Cancer Syndromes.

Fiasconaro CA et al.

Diseases (basel, Switzerland), 2025

Genetic Analysis of CYP1B1 and Other Anterior Segment Dysgenesis-Associated Genes in Latvian Cohort of Primary Congenital Glaucoma.

Elksne E et al.

Biomedicines, 2025

The importance of CYP1B1 polymorphism in obesity.

Cilekar M et al.

Medicine, 2025

Identification and structural analysis of pathogenic variants in MYOC and CYP1B1 genes in Indian JOAG patients.

Yadav M et al.

Japanese Journal of Ophthalmology, 2025

Heme-thiolate monooxygenase cytochrome P450 1B1, an old dog with many new tricks.

Kim JW et al.

Pharmacological Reviews, 2025

SNP's use as a potential chemotoxicity stratification tool in breast cancer: from bench to clinic.

Moustafa HAM et al.

Functional & Integrative Genomics, 2025

Pathogenic variants identification in primary congenital glaucoma patients using whole exome sequencing.

Ahmad S et al.

Scientific Reports, 2025

Whole exome sequencing reveals an FCGBP variant associated with spontaneous intraabdominal hemorrhage in severe acute pancreatitis.

Tang QY et al.

Imetaomics, 2025

41675706 (PubMed )
Supplement: IMO2-2-e52-s002.xlsx › 2D

Overall Survival in Male Patients With Advanced Hematological Disease (Mostly Acute Leukemia) Is Influenced by CYP1B1 C432G Polymorphism and Donor Sex in Allogeneic Stem Cell Transplantation.

Stute N et al.

American Journal of Hematology, 2025

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms: A Review.

Mokhosoev IM et al.

Cells, 2024

Low-Penetrance Susceptibility Variants in Colorectal Cancer-Current Outlook in the Field.

Szuman M et al.

International Journal of Molecular Sciences, 2024

Analysis of CYP1B1 Polymorphisms in Lung Cancer Patients Using Novel, Quick and Easy Methods Based on CAPS and ACRS-PCR Techniques.

Dąbrowski A et al.

International Journal of Molecular Sciences, 2024

Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-Analysis.

Liang YJ et al.

Jama Ophthalmology, 2024

Myocilin Mutation N480K Leads to Early Onset Juvenile and Adult-onset Primary Open Angle Glaucoma in a Six Generation Family.

Kader MA et al.

Journal of Glaucoma, 2024

Lower overall survival in male patients with advanced disease undergoing allogeneic hematopoietic stem cell transplantation is associated with CYP1B1 Leu432Val polymorphism.

Stute N et al.

Haematologica, 2024

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Single-nucleotide polymorphism in CYP1A1, CYP1B1, CYP2B6, CYP2C8, and CYP2C9 genes and their association with gastrointestinal cancer: A hospital-based case-control study.

Patil MN et al.

Journal of Cancer Research and Therapeutics, 2024

Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expression.

Kwon YJ et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2024

Single Nucleotide Polymorphisms Associated with Prostate Cancer Progression: A Systematic Review.

Mendivelso González DF et al.

Cancer Investigation, 2024

Genetic changes and testing associated with childhood glaucoma: A systematic review.

Kumar A et al.

Plos One, 2024

38386645 (PubMed )
Supplement: pone.0298883.s003.xlsx › Non-Case_Studies

Analysis of genetic biomarkers, polymorphisms in ADME-related genes and their impact on pharmacotherapy for prostate cancer.

Rehman K et al.

Cancer Cell International, 2023

Brain radiotoxicity-related 15CAcBRT gene expression signature predicts survival prognosis of glioblastoma patients.

Reyes-González J et al.

Neuro-oncology, 2023

35802478 (PubMed )
Supplement: noac171_suppl_suplementary_table_s1.xlsx › Table_S1

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.

Chamboko CR et al.

International Journal of Molecular Sciences, 2023

36834793 (PubMed )
Supplement: ijms-24-03383-s001.zip › ijms-2130595-supplementary.pdf

CYP1B1 and MYOC variants in neonatal-onset versus infantile-onset primary congenital glaucoma.

Kaushik S et al.

The British Journal of Ophthalmology, 2023

Pharmacogenetics of anxiety and depression in Alzheimer's disease.

Cacabelos R et al.

Pharmacogenomics, 2023

Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy.

Bagdasaryan AA et al.

Cancers, 2022

Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect.

Narendra G et al.

Clinical Pharmacokinetics, 2022

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM2_ESM.xlsx › Literature_review_table

Polymorphisms in CYP1B1 gene and the risk of suffering Primary Open-Angle Glaucoma: Systematic review and meta-analysis.

Calero-Dueñas N et al.

European Journal of Ophthalmology, 2022

Genetic variation at the catalytic subunit of glutamate cysteine ligase contributes to the susceptibility to sporadic colorectal cancer: a pilot study.

Bykanova MA et al.

Molecular Biology Reports, 2022

Genetic variants affecting chemical mediated skin immunotoxicity.

Rodrigues de Souza I et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2022

Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review.

Jemmeih S et al.

Ophthalmic Epidemiology, 2022

Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study.

Moitra P et al.

Journal of Neuro-oncology, 2022

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Genetic Susceptibility to Breast Cancer in Sub-Saharan African Populations.

Hayat M et al.

Jco Global Oncology, 2021

Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.

van Eijk M et al.

The Pharmacogenomics Journal, 2021

Influence of Pathogenic and Metabolic Genes on the Pharmacogenetics of Mood Disorders in Alzheimer's Disease.

Cacabelos R et al.

Pharmaceuticals (basel, Switzerland), 2021

Genetic Polymorphisms and Pharmacotherapy for Prostate Cancer.

Shiota M et al.

Jma Journal, 2021

Sequence Polymorphism in Xenobiotic Metabolising Genes in Iraqi Colorectal Cancer Patients.

Ibrahem SQ et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2021

Pathological characteristics, survival, and risk of breast cancer associated with estrogen and xenobiotic metabolism polymorphisms in Mexican women with breast cancer.

Martínez-Ramírez OC et al.

Cancer Causes & Control : Ccc, 2021

Genetic Susceptibility to Joint Occurrence of Polycystic Ovary Syndrome and Hashimoto's Thyroiditis: How Far Is Our Understanding?

Zeber-Lubecka N et al.

Frontiers in Immunology, 2021

Alpha-mannosidosis in Tunisian consanguineous families: Potential involvement of variants in GHR and SLC19A3 genes in the variable expressivity of cognitive impairment.

Mkaouar R et al.

Plos One, 2021

34614013 (PubMed )
Supplement: pone.0258202.s003.xlsx › Cognitive_impairment

Genetic Variations in Cytochrome P450 1A1 and 1B1 Genes in a Cohort of Patients from Iraq Diagnosed with Breast Cancer.

Ibrahem SQ et al.

Breast Cancer : Basic and Clinical Research, 2021

Genetic Variation and Hot Flashes: A Systematic Review.

Crandall CJ et al.

The Journal of Clinical Endocrinology and Metabolism, 2020

Association of cytochrome P450 1B1 gene polymorphisms and environmental biomarkers with hypertension in Slovak midlife women.

Falbová D et al.

Menopause (new York, N.y.), 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."