Varaico: Literature-Extracted Genetic Variants

Gene:CYP2A13
Variant:p.D158E
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CYP2A13

NM_000766.5:p.D158E

Associated Papers

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Waardenburg syndrome type 2 with a de novo variant of the SOX10 gene: a case report.

Li Y et al.

Bmc Medical Genomics, 2024

38659011 (PubMed )
Supplement: 12920_2024_1877_MOESM2_ESM.xlsx › H12056928648

Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.

Shimada T et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2018

Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.

Kumondai M et al.

Drug Metabolism and Pharmacokinetics, 2018

CYP2A13 Genetic Polymorphisms in Relation to the Risk of Bladder Cancer in Japanese Smokers.

Kumondai M et al.

Biological & Pharmaceutical Bulletin, 2016

An investigation of the catalytic activity of CYP2A13*4 with coumarin and polymorphisms of CYP2A13 in a Chinese Han population.

Liu T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2012

A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.

Wang LL et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009

Functional characterization of CYP2A13 polymorphisms.

Schlicht KE et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2007

The missense genetic polymorphisms of human CYP2A13: functional significance in carcinogen activation and identification of a null allelic variant.

Wang SL et al.

Toxicological Sciences : an Official Journal of the Society of Toxicology, 2006

Development of a real-time polymerase chain reaction-based method for the measurement of relative allelic expression and identification of CYP2A13 alleles with decreased expression in human lung.

Zhang X et al.

The Journal of Pharmacology and Experimental Therapeutics, 2004

Genetic polymorphism of the human cytochrome CYP2A13 in a French population: implication in lung cancer susceptibility.

Cauffiez C et al.

Biochemical and Biophysical Research Communications, 2004

Single nucleotide polymorphisms of the human cyp2a13 gene: evidence for a null allele.

Zhang X et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."