Varaico: Literature-Extracted Genetic Variants

Gene:CYP2A6
Variant:p.I359L
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CYP2A6

NM_000762.6:p.I359L

Associated Papers

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Advances in molecular modeling of human cytochrome P450 polymorphism.

Martiny VY et al.

Journal of Molecular Biology, 2013

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.

DeLozier TC et al.

The Journal of Pharmacology and Experimental Therapeutics, 2005

Pharmacogenomics in cardiovascular disease: the role of single nucleotide polymorphisms in improving drug therapy.

Mango R et al.

Expert Opinion on Pharmacotherapy, 2005

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.

Kim K et al.

Journal of Clinical Pharmacology, 2004

Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis.

Takada K et al.

Arthritis and Rheumatism, 2004

Evaluation of a microarray for genotyping polymorphisms related to xenobiotic metabolism and DNA repair.

Landi S et al.

Biotechniques, 2003

Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity.

Wormhoudt LW et al.

Critical Reviews in Toxicology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."