Varaico: Literature-Extracted Genetic Variants

Gene:CYP2A6
Variant:p.N262S
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CYP2A6

NM_000762.6:p.N262S

Associated Papers

Association of CYP2B6 and OPRM1 Genotypes with Methadone Dose Requirements and Serum Concentrations in a Vietnamese Cohorts.

Nguyen QG et al.

Balkan Journal of Medical Genetics : Bjmg, 2025

Severe and prolonged cyclophosphamide-induced hepatotoxicity in a breast cancer patient carrying a CYP2B6*7 variant.

Ming Z et al.

Pharmacogenomics, 2019

Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry.

Wang PF et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2019

Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes.

Gao N et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2016

PharmGKB summary: Efavirenz pathway, pharmacokinetics.

McDonagh EM et al.

Pharmacogenetics and Genomics, 2015

CYP2B6 gene single-nucleotide polymorphisms in an Italian population sample and relationship with nicotine dependence.

Riccardi LN et al.

Genetic Testing and Molecular Biomarkers, 2015

Allele and genotype frequencies of CYP2B6 in a Turkish population.

Yuce-Artun N et al.

Molecular Biology Reports, 2014

CYP2B6 haplotype and biological factors responsible for hepatotoxicity in HIV-infected patients receiving efavirenz-based antiretroviral therapy.

Manosuthi W et al.

International Journal of Antimicrobial Agents, 2014

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Frequencies of Cytochrome P450 2B6 and 2C8 Allelic Variants in the Mozambican Population.

Arnaldo P et al.

The Malaysian Journal of Medical Sciences : Mjms, 2013

Impact of pharmacogenetic markers of CYP2B6, clinical factors, and drug-drug interaction on efavirenz concentrations in HIV/tuberculosis-coinfected patients.

Manosuthi W et al.

Antimicrobial Agents and Chemotherapy, 2013

Cytochrome P450 variations in different ethnic populations.

McGraw J et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients.

Tan L et al.

Clinical Neurology and Neurosurgery, 2010

CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial.

Lee AM et al.

Biological Psychiatry, 2007

Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.

Saussele T et al.

Clinical Pharmacology and Therapeutics, 2007

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T et al.

Pharmacogenetics, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."