Varaico: Literature-Extracted Genetic Variants

Gene:CYP2A6
Variant:p.G5R
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CYP2A6

NM_000762.6:p.G5R

Associated Papers

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

PharmVar GeneFocus: CYP2A6.

Langlois AWR et al.

Clinical Pharmacology and Therapeutics, 2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM2_ESM.xlsx › Sheet1

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.

Hosono H et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2017

Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.

López-Flores LA et al.

Excli Journal, 2017

A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.

Wang LL et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009

Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations.

Nakajima M et al.

Clinical Pharmacology and Therapeutics, 2006

Three haplotypes associated with CYP2A6 phenotypes in Caucasians.

Haberl M et al.

Pharmacogenetics and Genomics, 2005

Characterization of novel CYP2A6 polymorphic alleles (CYP2A6*18 and CYP2A6*19) that affect enzymatic activity.

Fukami T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005

Novel human CYP2A6 alleles confound gene deletion analysis.

Nakajima M et al.

Febs Letters, 2004

Twenty one novel single nucleotide polymorphisms (SNPs) of the CYP2A6 gene in Japanese and Caucasians.

Kiyotani K et al.

Drug Metabolism and Pharmacokinetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."