Varaico: Literature-Extracted Genetic Variants

Gene:CYP2A7
Variant:p.I471T
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CYP2A7

NM_000764.3:p.I471T

Associated Papers

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

41298791 (PubMed )
Supplement: 41598_2025_26258_MOESM3_ESM.docx

Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.

Hosono H et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2017

Pharmacogenetics of nicotine and associated smoking behaviors.

Tanner JA et al.

Current Topics in Behavioral Neurosciences, 2015

Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

Zanger UM et al.

Pharmacology & Therapeutics, 2013

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line.

Lee HJ et al.

Toxicological Research, 2011

The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.

Ferraro TN et al.

Epilepsy & Behavior : E&b, 2005

Nicotine metabolism, human drug metabolism polymorphisms, and smoking behaviour.

Tricker AR

Toxicology, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."