Associated Papers
Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.
Hosono H et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2017
Pharmacogenetics of nicotine and associated smoking behaviors.
Tanner JA et al.
Current Topics in Behavioral Neurosciences, 2015
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.
Loukola A et al.
Plos Genetics, 2015
26407342 (PubMed )
Supplement: pgen.1005498.s011.xlsx › S2_table
Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.
Lee IS et al.
Archives of Pharmacal Research, 2011
A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo.
Al Koudsi N et al.
The Pharmacogenomics Journal, 2009
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.
Ferraro TN et al.
Epilepsy & Behavior : E&b, 2005
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