Varaico: Literature-Extracted Genetic Variants

Gene:CYP2B6
Variant:p.R29P
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CYP2B6

NM_000767.5:p.R29P

Associated Papers

Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.

Yang W et al.

Jama Network Open, 2022

36580335 (PubMed )
Supplement: jamanetwopen-e2248803-s001.pdf

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Sequencing of a central nervous system tumor demonstrates cancer transmission in an organ transplant.

Gingras MC et al.

Life Science Alliance, 2021

34301805 (PubMed )
Supplement: LSA-2020-00941_TableS4.xlsx › Table_S4

Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry.

Wang PF et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2019

PRIMA-1MET-induced neuroblastoma cell death is modulated by p53 and mycn through glutathione level.

Mlakar V et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2019

30755224 (PubMed )
Supplement: 13046_2019_1066_MOESM1_ESM.xlsx › NGP

Stereoselective Ketamine Metabolism by Genetic Variants of Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase.

Wang PF et al.

Anesthesiology, 2018

Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers.

Cho DY et al.

Drug Metabolism and Pharmacokinetics, 2016

Pharmacogenetics of antiretroviral therapy.

Barreiro P et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Allele and genotype frequencies of CYP2B6 in a Turkish population.

Yuce-Artun N et al.

Molecular Biology Reports, 2014

Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection.

Jamshidi Y et al.

The Journal of Antimicrobial Chemotherapy, 2010

A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.

Wang LL et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009

Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals.

Rotger M et al.

Clinical Pharmacology and Therapeutics, 2007

MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms.

Blievernicht JK et al.

Clinical Chemistry, 2007

Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese.

Guan S et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2006

Intra- and inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese.

Guan S et al.

Pharmaceutical Research, 2006

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz.

Klein K et al.

Pharmacogenetics and Genomics, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."