Varaico: Literature-Extracted Genetic Variants

Gene:CYP2B6
Variant:p.I114T
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CYP2B6

NM_000767.5:p.I114T

Associated Papers

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

Multidisciplinary Insights into the Structure-Function Relationship of the CYP2B6 Active Site.

Angle ED et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Effects of cytochrome P450 2B6 and constitutive androstane receptor genetic variation on Efavirenz plasma concentrations among HIV patients in Kenya.

Ngayo MO et al.

Plos One, 2022

Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers.

Seng KY et al.

Antimicrobial Agents and Chemotherapy, 2015

Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine.

Čolić A et al.

Drug Metabolism Reviews, 2015

Novel CYP2B6 enzyme variants in a Rwandese population: functional characterization and assessment of in silico prediction tools.

Radloff R et al.

Human Mutation, 2013

Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection.

Jamshidi Y et al.

The Journal of Antimicrobial Chemotherapy, 2010

Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer.

Gresner P et al.

Lung Cancer (amsterdam, Netherlands), 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."