Varaico: Literature-Extracted Genetic Variants

Gene:CYP2B6
Variant:p.G432Splc
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CYP2B6

NM_000767.5:p.G432Splc

Associated Papers

CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel.

Ramste M et al.

Clinical and Translational Science, 2023

Pharmacogenetics of Antiplatelet Therapy.

Castrichini M et al.

Annual Review of Pharmacology and Toxicology, 2023

Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.

Lewis JP et al.

European Heart Journal. Cardiovascular Pharmacotherapy, 2020

The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa.

Song Q et al.

Scientific Reports, 2015

Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study.

Dobrinas M et al.

Pharmacogenetics and Genomics, 2013

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz.

Klein K et al.

Pharmacogenetics and Genomics, 2005

Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles.

Lang T et al.

The Journal of Pharmacology and Experimental Therapeutics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."