Varaico: Literature-Extracted Genetic Variants

Gene:CYP2B6
Variant:p.C475S
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CYP2B6

NM_000767.5:p.C475S

Associated Papers

Multidisciplinary Insights into the Structure-Function Relationship of the CYP2B6 Active Site.

Angle ED et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023

Polymorphisms of cytochrome P450 2B6 (CYP2B6) in cynomolgus and rhesus macaques.

Uno Y et al.

Journal of Medical Primatology, 2018

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos.

D'Agostino J et al.

Chemical Research in Toxicology, 2015

Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules.

Shah MB et al.

Biochemistry, 2012

Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of heme.

Zhang H et al.

Molecular Pharmacology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."