Associated Papers
CYP2C19 genotype-guided dosing of proton pump inhibitors: progress in clinical trials and real-world use.
Thuy HM et al.
Expert Review of Clinical Pharmacology, 2026
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.
Park K et al.
Laboratory Medicine, 2024
Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.
Scott SA et al.
Clinical and Translational Science, 2021
32931151 (PubMed )
Supplement: CTS-14-204-s001.xlsx › Table_S1
Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine.
Brown SA et al.
Journal of Personalized Medicine, 2018
Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.
Isvoran A et al.
Drug Discovery Today, 2017
Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation.
Takahashi M et al.
The Pharmacogenomics Journal, 2015
Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.
Helsby NA et al.
Frontiers in Genetics, 2012
Evaluation of the effects of 18 non-synonymous single-nucleotide polymorphisms of CYP450 2C19 on in vitro drug inhibition potential by a fluorescence-based high-throughput assay.
Wang H et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2011
Evaluation of the effects of 20 nonsynonymous single nucleotide polymorphisms of CYP2C19 on S-mephenytoin 4'-hydroxylation and omeprazole 5'-hydroxylation.
Wang H et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2011
Functional characterization of two novel CYP2C19 variants (CYP2C19*18 and CYP2C19*19) found in a Japanese population.
Hanioka N et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2007
Genetic variations and haplotypes of CYP2C19 in a Japanese population.
Fukushima-Uesaka H et al.
Drug Metabolism and Pharmacokinetics, 2005
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