Associated Papers
Cytochrome P450 1A1, 2C9, 2C19, and 3A4 Polymorphisms Account for Interindividual Variability of Toxicological Drug Metabolism in Cynomolgus Macaques.
Uno Y et al.
Chemical Research in Toxicology, 2018
Genetic polymorphisms of drug-metabolizing cytochrome P450 enzymes in cynomolgus and rhesus monkeys and common marmosets in preclinical studies for humans.
Uno Y et al.
Biochemical Pharmacology, 2018
R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys.
Utoh M et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2018
Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers.
Uehara S et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2016
Development of a genotyping tool for a functionally relevant CYP2C19 allele (Phe100Asn, Ala103Val and Ile112Leu) in cynomolgus macaques.
Uno Y et al.
The Journal of Veterinary Medical Science, 2016
Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.
Utoh M et al.
Biochemical Pharmacology, 2015
Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9.
Uno Y et al.
Drug Metabolism and Pharmacokinetics, 2015
CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques.
Uno Y et al.
Biochemical Pharmacology, 2014
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