Associated Papers
In vitro assessment of the impact of 30 CYP2C19 variants on citalopram metabolism.
Wang P et al.
Peerj, 2025
CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism.
Ye Z et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024
APF2: an improved ensemble method for pharmacogenomic variant effect prediction.
Zhou Y et al.
The Pharmacogenomics Journal, 2024
Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach.
Avsar O
Nucleosides, Nucleotides & Nucleic Acids, 2024
Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism.
Yuan LJ et al.
Toxicology and Applied Pharmacology, 2023
Effects of CYP2C19 variants on the metabolism of tapentadol in vitro.
Xu RA et al.
Iranian Journal of Basic Medical Sciences, 2022
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.
Silgado-Guzmán DF et al.
Frontiers in Pharmacology, 2022
Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.
Lan T et al.
Journal of Psychopharmacology (oxford, England), 2021
Han Chinese specific cytochrome P450 polymorphisms and their impact on the metabolism of anti-hypertensive drugs with adrenoreceptor blocking properties.
Qian JC et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.
Zhang L et al.
Clinical and Translational Science, 2020
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Zhou Y et al.
The Pharmacogenomics Journal, 2019
Functional characterization of CYP2C19 variants in nebivolol 4-hydroxlation in vitro.
Zhou XY et al.
Drug Testing and Analysis, 2018
The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro.
Xu RA et al.
Infection and Drug Resistance, 2018
Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
Zhou Y et al.
Clinical Pharmacology and Therapeutics, 2017
Effects of CYP2C19 variants on methadone metabolism in vitro.
Lan T et al.
Drug Testing and Analysis, 2017
Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.
Fang P et al.
Pharmacology, 2017