Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.R125H
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CYP2C19

NM_000769.4:p.R125H

Associated Papers

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Goljan E et al.

Plos One, 2022

35089958 (PubMed )
Supplement: pone.0263137.s002.xlsx › Sheet1

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

Systematic analysis of the intersection of disease mutations with protein modifications.

Simpson CM et al.

Bmc Medical Genomics, 2019

31345222 (PubMed )
Supplement: 12920_2019_543_MOESM2_ESM.xlsx › S2

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content.

Shirasaka Y et al.

The Pharmacogenomics Journal, 2016

Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Zhou SF et al.

Toxicology, 2010

Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.

DeLozier TC et al.

The Journal of Pharmacology and Experimental Therapeutics, 2005

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.

Zhao F et al.

Clinical Pharmacology and Therapeutics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."