Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.Q192R
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CYP2C19

NM_000769.4:p.Q192R

Associated Papers

The association of CYP2C19 LoF alleles with adverse clinical outcomes in stroke patients taking clopidogrel: An updated meta-analysis.

Biswas M et al.

Clinical and Translational Science, 2024

A Pharmacogenetic Study of CYP2C19 in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel Therapy.

Angulo-Aguado M et al.

Journal of Personalized Medicine, 2021

PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study.

Tanaka K et al.

Plos One, 2021

The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention.

Zhang Z et al.

Bmc Pharmacology & Toxicology, 2020

Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease.

Tresukosol D et al.

Plos One, 2014

Genetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients.

Zhang L et al.

Thrombosis Research, 2013

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Kreutz RP et al.

Clinical Pharmacology : Advances and Applications, 2013

Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review).

Martino A et al.

International Journal of Oncology, 2012

Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions?

Ma TK et al.

British Journal of Clinical Pharmacology, 2011

Clinically relevant genetic variations in drug metabolizing enzymes.

Pinto N et al.

Current Drug Metabolism, 2011

Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

Simoni M et al.

Human Reproduction Update, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."