Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.R206R
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CYP2C19

NM_000769.4:p.R206R

Associated Papers

Pharmacogenetic influence on bupropion bioactivation and clinical outcomes in major depressive disorder.

Kharasch ED et al.

The Journal of Pharmacology and Experimental Therapeutics, 2026

Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion.

Kharasch ED et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024

Methadone pharmacogenetics in vitro and in vivo: Metabolism by CYP2B6 polymorphic variants and genetic variability in paediatric disposition.

Wang PF et al.

British Journal of Clinical Pharmacology, 2022

Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.

Muyambo S et al.

Omics : a Journal of Integrative Biology, 2022

Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients.

Lim JS et al.

British Journal of Clinical Pharmacology, 2016

Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel.

Zabalza M et al.

Heart (british Cardiac Society), 2012

Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles.

Kim KA et al.

Journal of Clinical Pharmacy and Therapeutics, 2010

Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy.

Pinto N et al.

Pharmacogenomics, 2009

Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition.

Hines RN et al.

Drug Metabolism Reviews, 2008

Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: an update.

Cressey TR et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."