Associated Papers
Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.
Boyle GE et al.
Genetics, 2024
Novel Cytochrome P450 2C94 Functionally Metabolizes Diclofenac and Omeprazole in Dogs.
Uno Y et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023
CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.
Zhang L et al.
Clinical and Translational Science, 2020
Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.
Uehara S et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2015
Effect of cytochrome P450 2C19 and 2C9 amino acid residues 72 and 241 on metabolism of tricyclic antidepressant drugs.
Attia TZ et al.
Chemical & Pharmaceutical Bulletin, 2014
Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.
Wada Y et al.
Journal of Biochemistry, 2008
Select a paper to view details