Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.D256N
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CYP2C19

NM_000769.4:p.D256N

Associated Papers

Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.

Park K et al.

Laboratory Medicine, 2024

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

32931151 (PubMed )
Supplement: CTS-14-204-s001.xlsx › Table_S1

Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine.

Brown SA et al.

Journal of Personalized Medicine, 2018

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.

Isvoran A et al.

Drug Discovery Today, 2017

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

Hiratsuka M

Biological & Pharmaceutical Bulletin, 2016

Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation.

Takahashi M et al.

The Pharmacogenomics Journal, 2015

Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.

Helsby NA et al.

Frontiers in Genetics, 2012

Clinical Application of CYP2C19 Pharmacogenetics Toward More Personalized Medicine.

Lee SJ

Frontiers in Genetics, 2012

Pharmacogenomics of clopidogrel: evidence and perspectives.

Yin T et al.

Thrombosis Research, 2011

Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole.

Lee SJ et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."