Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.K273_E274Splc
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CYP2C19

NM_000769.4:p.K273_E274Splc

Associated Papers

Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency.

Hedberg-Oldfors C et al.

Acta Neuropathologica, 2024

39586906 (PubMed )
Supplement: 401_2024_2830_MOESM1_ESM.pdf

A New Cloud-Native Tool for Pharmacogenetic Analysis.

Yuan DY et al.

Genes, 2024

38540411 (PubMed )
Supplement: genes-15-00352-s001.zip › Pgxtools__a_new_cloud-native_tool_for_Pharmacogenetic_analysis-Supplemental-1-revised.pdf

Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.

Park K et al.

Laboratory Medicine, 2024

Polymorphisms of genes related to phase-I metabolic enzymes affecting the clinical efficacy and safety of clopidogrel treatment.

Alkattan A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2021

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

32931151 (PubMed )
Supplement: CTS-14-204-s001.xlsx › Table_S1

Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation.

García-García I et al.

Frontiers in Pharmacology, 2021

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.

Cao Y et al.

Cell Research, 2020

CYP2C19 Genotype is an Independent Predictor of Adverse Cardiovascular Outcome in Iraqi Patients on Clopidogrel After Percutaneous Coronary Intervention.

Mohammad AM et al.

Journal of Cardiovascular Pharmacology, 2018

Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2018

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.

Ng D et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017

27537706 (PubMed )
Supplement: NIHMS802548-supplement-Table_S4.pdf

Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation.

Goh LL et al.

Plos One, 2017

CYP2C19 genetic polymorphism in Saudi Arabians.

Al-Jenoobi FI et al.

Basic & Clinical Pharmacology & Toxicology, 2013

CYP2C19 variation and citalopram response.

Mrazek DA et al.

Pharmacogenetics and Genomics, 2011

Intronic polymorphisms of cytochromes P450.

Ingelman-Sundberg M et al.

Human Genomics, 2010

Implementing genotype-guided antithrombotic therapy.

Seip RL et al.

Future Cardiology, 2010

Genotyping panel for assessing response to cancer chemotherapy.

Dai Z et al.

Bmc Medical Genomics, 2008

18547414 (PubMed )
Supplement: 1755-8794-1-24-S1.xls › SNPs_selected_for_SNPlex_design

Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays.

Melis R et al.

Expert Review of Molecular Diagnostics, 2006

The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives.

Sim SC et al.

Methods in Molecular Biology (clifton, N.j.), 2006

Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

Rogan PK et al.

Pharmacogenetics, 2003

The Human Cytochrome P450 Allele Nomenclature Committee Web Site : Submission Criteria, Procedures, and Objectives.

Sim SC et al.

Methods in Molecular Biology (clifton, N.j.), 0

Feasibility of clinical pharmacist-led CYP2C19 genotyping for patients receiving non-emergent cardiac catheterization in an integrated health system.

Johnson SG et al.

Pharmacy Practice, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."