Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.I327T
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CYP2C19

NM_000769.4:p.I327T

Associated Papers

In vitro assessment of the impact of 30 CYP2C19 variants on citalopram metabolism.

Wang P et al.

Peerj, 2025

CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism.

Ye Z et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM2_ESM.xlsx › Sheet1

Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism.

Yuan LJ et al.

Toxicology and Applied Pharmacology, 2023

Effects of CYP2C19 variants on the metabolism of tapentadol in vitro.

Xu RA et al.

Iranian Journal of Basic Medical Sciences, 2022

Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.

Lan T et al.

Journal of Psychopharmacology (oxford, England), 2021

Functional characterization of CYP2C19 variants in nebivolol 4-hydroxlation in vitro.

Zhou XY et al.

Drug Testing and Analysis, 2018

The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro.

Xu RA et al.

Infection and Drug Resistance, 2018

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Effects of CYP2C19 variants on methadone metabolism in vitro.

Lan T et al.

Drug Testing and Analysis, 2017

Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.

Fang P et al.

Pharmacology, 2017

In vitro functional analysis of 24 novel CYP2C19 variants recently found in the Chinese Han population.

Dai DP et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2015

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Zhou SF et al.

Toxicology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."