Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.D341N
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CYP2C19

NM_000769.4:p.D341N

Associated Papers

In vitro assessment of the impact of 30 CYP2C19 variants on citalopram metabolism.

Wang P et al.

Peerj, 2025

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM2_ESM.xlsx › Sheet1

Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism.

Yuan LJ et al.

Toxicology and Applied Pharmacology, 2023

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Recognition of functional genetic polymorphism using ESE motif definition: a conservative evolutionary approach to CYP2D6/CYP2C19 gene variants.

Samadi M et al.

Genetica, 2022

Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.

Lan T et al.

Journal of Psychopharmacology (oxford, England), 2021

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

Zhou Y et al.

The Pharmacogenomics Journal, 2019

30206299 (PubMed )
Supplement: 41397_2018_44_MOESM5_ESM.xlsx › Sheet1

Functional characterization of CYP2C19 variants in nebivolol 4-hydroxlation in vitro.

Zhou XY et al.

Drug Testing and Analysis, 2018

The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro.

Xu RA et al.

Infection and Drug Resistance, 2018

Effects of CYP2C19 variants on methadone metabolism in vitro.

Lan T et al.

Drug Testing and Analysis, 2017

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.

Ng D et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2017

27537706 (PubMed )
Supplement: NIHMS802548-supplement-Table_S4.pdf

Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.

Fang P et al.

Pharmacology, 2017

In vitro functional analysis of 24 novel CYP2C19 variants recently found in the Chinese Han population.

Dai DP et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."