Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C19
Variant:p.E444Q
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CYP2C19

NM_000769.4:p.E444Q

Associated Papers

Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.

Boyle GE et al.

Genetics, 2024

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.

Seo ME et al.

Frontiers in Pharmacology, 2023

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."