Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C8
Variant:p.H411L
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CYP2C8

NM_000770.3:p.H411L

Associated Papers

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.

Totah RA et al.

Clinical Pharmacology and Therapeutics, 2005

A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin.

Ishikawa C et al.

Journal of Human Genetics, 2004

Genetic polymorphisms of CYP2C8 in Japanese population.

Nakajima M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."