Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C8
Variant:p.I244V
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CYP2C8

NM_000770.3:p.I244V

Associated Papers

Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.

Prost R et al.

International Journal of Molecular Sciences, 2025

Functional Characterization of Allelic Variations of Human Cytochrome P450 2C8 (V181I, I244V, I331T, and L361F).

Lee YB et al.

International Journal of Molecular Sciences, 2023

CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project.

Gaedigk A et al.

The Journal of Molecular Diagnostics : Jmd, 2022

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.

Backman JT et al.

Pharmacological Reviews, 2016

Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies.

Daily EB et al.

Pharmacogenomics, 2009

Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

Agúndez JA et al.

Expert Opinion on Drug Metabolism & Toxicology, 2009

The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.

Ferraro TN et al.

Epilepsy & Behavior : E&b, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."