Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C8
Variant:p.T130N
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CYP2C8

NM_000770.3:p.T130N

Associated Papers

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.

Backman JT et al.

Pharmacological Reviews, 2016

Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1.

Nakajima M et al.

Journal of Clinical Pharmacology, 2005

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.

Totah RA et al.

Clinical Pharmacology and Therapeutics, 2005

A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin.

Ishikawa C et al.

Journal of Human Genetics, 2004

Genetic polymorphisms of CYP2C8 in Japanese population.

Nakajima M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."