Associated Papers
Effect of cytochrome P450 2C19 and 2C9 amino acid residues 72 and 241 on metabolism of tricyclic antidepressant drugs.
Attia TZ et al.
Chemical & Pharmaceutical Bulletin, 2014
Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.
Wada Y et al.
Journal of Biochemistry, 2008
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
Davies C et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004
Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.
Lewis DF et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 1998
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