Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.W120R
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CYP2C9

NM_000771.4:p.W120R

Associated Papers

Impact of single nucleotide polymorphisms (R132Q and W120R) on the binding affinity and metabolic activity of CYP2C19 toward some therapeutically important substrates.

Derayea SM et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.

Isvoran A et al.

Drug Discovery Today, 2017

Pharmacogenetics in Jewish populations.

Yang Y et al.

Drug Metabolism and Drug Interactions, 2014

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Novel drug metabolism indices for pharmacogenetic functional status based on combinatory genotyping of CYP2C9, CYP2C19 and CYP2D6 genes.

Villagra D et al.

Biomarkers in Medicine, 2011

The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population.

Liou YH et al.

Journal of Human Genetics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."