Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.I123N
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CYP2C9

NM_000771.4:p.I123N

Associated Papers

Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state.

Li S et al.

Blood Advances, 2023

Identification of VKORC1 genotype leading to resistance to tecarfarin.

Matagrin B et al.

Journal of Clinical Pharmacology, 2014

VKORC1 mutations detected in patients resistant to vitamin K antagonists are not all associated with a resistant VKOR activity.

Hodroge A et al.

Journal of Thrombosis and Haemostasis : Jth, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."