Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.L128R
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CYP2C9

NM_000771.4:p.L128R

Associated Papers

Frequencies of CYP2C9 polymorphisms in a Syrian cohort.

Aldiban W et al.

Bmc Genomics, 2025

Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state.

Li S et al.

Blood Advances, 2023

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Pharmacogenetics in Jewish populations.

Yang Y et al.

Drug Metabolism and Drug Interactions, 2014

Novel associations of VKORC1 variants with higher acenocoumarol requirements.

Anton AI et al.

Plos One, 2013

VKORC1 mutations detected in patients resistant to vitamin K antagonists are not all associated with a resistant VKOR activity.

Hodroge A et al.

Journal of Thrombosis and Haemostasis : Jth, 2012

Pharmacogenetics in cardiovascular antithrombotic therapy.

Marín F et al.

Journal of the American College of Cardiology, 2009

CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.

Scott SA et al.

Pharmacogenomics, 2009

Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans.

Bodin L et al.

Journal of Thrombosis and Haemostasis : Jth, 2008

Building individualized medicine: prevention of adverse reactions to warfarin therapy.

Krynetskiy E et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."