Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.T130M
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CYP2C9

NM_000771.4:p.T130M

Associated Papers

CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism.

Ye Z et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM1_ESM.xlsx › Sheet1

Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach.

Avsar O

Nucleosides, Nucleotides & Nucleic Acids, 2024

Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism.

Yuan LJ et al.

Toxicology and Applied Pharmacology, 2023

Enzymatic activity of 38 CYP2C9 genotypes on ibuprofen.

Yuan LJ et al.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 2023

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Goljan E et al.

Plos One, 2022

Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.

Lan T et al.

Journal of Psychopharmacology (oxford, England), 2021

Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.

Neyshaburinezhad N et al.

Journal of Personalized Medicine, 2021

34442448 (PubMed )
Supplement: jpm-11-00804-s001.zip › jpm-1270394-supplementary.pdf

Functional Assessment of 12 Rare Allelic CYP2C9 Variants Identified in a Population of 4773 Japanese Individuals.

Kumondai M et al.

Journal of Personalized Medicine, 2021

33540768 (PubMed )
Supplement: jpm-11-00094-s001.pdf

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism.

Tang PF et al.

Drug Design, Development and Therapy, 2020

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Effects of CYP2C19 variants on methadone metabolism in vitro.

Lan T et al.

Drug Testing and Analysis, 2017

Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.

Fang P et al.

Pharmacology, 2017

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

Hiratsuka M

Biological & Pharmaceutical Bulletin, 2016

Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9.

Uno Y et al.

Drug Metabolism and Pharmacokinetics, 2015

Impact of CYP2C9 polymorphism found in the Chinese population on the metabolism of propofol in vitro.

Lian QQ et al.

Biological & Pharmaceutical Bulletin, 2015

CYP2C9 polymorphism analysis in Han Chinese populations: building the largest allele frequency database.

Dai DP et al.

The Pharmacogenomics Journal, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."