Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.R132W
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CYP2C9

NM_000771.4:p.R132W

Associated Papers

Cytochrome P450 F-helix N204H mutation in CYP2C9.57 genetic variant reveals non-typical ligand binding properties.

Kisel M et al.

Febs Letters, 2025

Frequencies of CYP2C9 polymorphisms in a Syrian cohort.

Aldiban W et al.

Bmc Genomics, 2025

The relationship between CYP2C9 gene polymorphisms and azilsartan metabolism in vitro.

Bao SS et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM1_ESM.xlsx › Sheet1

Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach.

Avsar O

Nucleosides, Nucleotides & Nucleic Acids, 2024

Enzymatic activity of 38 CYP2C9 genotypes on ibuprofen.

Yuan LJ et al.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 2023

Identification and in vitro functional assessment of 10 CYP2C9 variants found in Chinese Han subjects.

Zhang Q et al.

Frontiers in Endocrinology, 2023

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Goljan E et al.

Plos One, 2022

Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data.

Neyshaburinezhad N et al.

Journal of Personalized Medicine, 2021

34442448 (PubMed )
Supplement: jpm-11-00804-s001.zip › jpm-1270394-supplementary.pdf

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions.

Calderon-Ospina CA et al.

Pharmacogenomics and Personalized Medicine, 2020

Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism.

Tang PF et al.

Drug Design, Development and Therapy, 2020

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

The role of CYP2C9 genetic polymorphism in carvedilol O-desmethylation in vitro.

Pan PP et al.

European Journal of Drug Metabolism and Pharmacokinetics, 2016

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

Hiratsuka M

Biological & Pharmaceutical Bulletin, 2016

Impact of CYP2C9 polymorphism found in the Chinese population on the metabolism of propofol in vitro.

Lian QQ et al.

Biological & Pharmaceutical Bulletin, 2015

The role of CYP2C9 genetic polymorphisms in the oxidative metabolism of diclofenac in vitro.

Xia MM et al.

Die Pharmazie, 2014

CYP2C9 polymorphism analysis in Han Chinese populations: building the largest allele frequency database.

Dai DP et al.

The Pharmacogenomics Journal, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."