Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.R144H
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CYP2C9

NM_000771.4:p.R144H

Associated Papers

Frequencies of CYP2C9 polymorphisms in a Syrian cohort.

Aldiban W et al.

Bmc Genomics, 2025

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

PharmVar GeneFocus: CYP2C9.

Sangkuhl K et al.

Clinical Pharmacology and Therapeutics, 2021

CYP2C9 Variations and Their Pharmacogenetic Implications Among Diverse South Asian Populations.

Nizamuddin S et al.

Pharmacogenomics and Personalized Medicine, 2021

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Zhang L et al.

Clinical and Translational Science, 2020

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.

Isvoran A et al.

Drug Discovery Today, 2017

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips.

Nakamoto K et al.

Pharmacogenetics and Genomics, 2007

The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population.

Liou YH et al.

Journal of Human Genetics, 2006

Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.

Tranah GJ et al.

Molecular Carcinogenesis, 2005

Identification and functional characterization of new potentially defective alleles of human CYP2C19.

Blaisdell J et al.

Pharmacogenetics, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."