Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.K206E
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CYP2C9

NM_000771.4:p.K206E

Associated Papers

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30.

Louet M et al.

Plos One, 2018

Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin.

Lertkiatmongkol P et al.

Plos One, 2013

Mechanism of the decrease in catalytic activity of human cytochrome P450 2C9 polymorphic variants investigated by computational analysis.

Sano E et al.

Journal of Computational Chemistry, 2010

Multiple molecular dynamics simulations of human p450 monooxygenase CYP2C9: the molecular basis of substrate binding and regioselectivity toward warfarin.

Seifert A et al.

Proteins, 2006

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution.

Wester MR et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."