Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.L208V
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CYP2C9

NM_000771.4:p.L208V

Associated Papers

Identification and Enzymatic Activity Evaluation of a Novel CYP2C9 Allelic Variant Discovered in a Patient.

Zhou XY et al.

Frontiers in Pharmacology, 2021

Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Zhou SF et al.

Toxicology, 2010

CYP2C9 amino acid residues influencing phenytoin turnover and metabolite regio- and stereochemistry.

Mosher CM et al.

The Journal of Pharmacology and Experimental Therapeutics, 2009

CYP2C9 polymorphism in non-steroidal anti-inflammatory drugs-induced gastropathy.

Ma J et al.

Journal of Digestive Diseases, 2008

Polymorphisms in xenobiotic-metabolizing genes and the risk of chronic lymphocytic leukemia and non-Hodgkin's lymphoma in adult Russian patients.

Gra OA et al.

American Journal of Hematology, 2008

Factors affecting the maintenance stable warfarin dosage in Hong Kong Chinese patients.

Lee VW et al.

Journal of Thrombosis and Thrombolysis, 2005

No exon 4 polymorphism of cytochrome P450 CYP2C9 in Taiwanese.

Chang JG

Blood, 2003

Polymorphism induced sensitivity to warfarin: a review of the literature.

Palkimas MP et al.

Journal of Thrombosis and Thrombolysis, 2003

CYP2C9 exon 4 mutations and warfarin dose phenotype in Asians.

Rettie AE et al.

Blood, 2003

Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin.

Takahashi H et al.

The Pharmacogenomics Journal, 2003

A valine deletion of ferroportin 1: a common mutation in hemochromastosis type 4.

Roetto A et al.

Blood, 2002

Leu208Val and Ile181Leu variants of cytochrome P450 CYP2C9 are not related to the acenocoumarol dose requirement in a Spanish population.

Zarza J et al.

Blood, 2002

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy.

Higashi MK et al.

Jama, 2002

Genetic polymorphism in exon 4 of cytochrome P450 CYP2C9 may be associated with warfarin sensitivity in Chinese patients.

Leung AY et al.

Blood, 2001

Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole activity.

Ibeanu GC et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."