Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.W212*
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CYP2C9

NM_000771.4:p.W212*

Associated Papers

Cytochrome P450 17 (CYP17), CYP2C19*2, CYP2C19*3 Gene Polymorphisms and Gastrointestinal Cancer Risk in Rural Maharashtra: A Hospital based Case-Control Study.

Datkhile KD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

Effect of CYP2C19 polymorphism on response to bortezomib-based therapy in multiple myeloma patients.

Goel L et al.

The American Journal of the Medical Sciences, 2024

CYP2C19*17 association with higher plasma 4-hydroxy tamoxifen in Pakistani (estrogen-positive) breast cancer patients.

Tareen MU et al.

Experimental Biology and Medicine (maywood, N.j.), 2023

Cytochrome P450 2C19 gene polymorphisms (CYP2C19*2 and CYP2C19*3) in chronic myeloid leukemia patients: in vitro and in silico studies.

Joshi K et al.

Journal of Biomolecular Structure & Dynamics, 2022

Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.

Lan T et al.

Journal of Psychopharmacology (oxford, England), 2021

Impact of CYP2C19, CYP3A4, ABCB1, and FMO3 genotypes on plasma voriconazole in Thai patients with invasive fungal infections.

Chuwongwattana S et al.

Pharmacology Research & Perspectives, 2020

CYP2C19 Allele Frequencies in Over 2.2 Million Direct-to-Consumer Genetics Research Participants and the Potential Implication for Prescriptions in a Large Health System.

Ionova Y et al.

Clinical and Translational Science, 2020

CYP2C9, CYP2C19, CYP2D6 and CYP3A5 polymorphisms in South-East and East Asian populations: A systematic review.

Dorji PW et al.

Journal of Clinical Pharmacy and Therapeutics, 2019

The Prognostic Value of Combinations of Genetic Polymorphisms in the ITGB3, ITGA2, and CYP2C19*2 Genes in Predicting Cardiovascular Outcomes After Coronary Bypass Grafting.

Grinshtein YI et al.

Genetic Testing and Molecular Biomarkers, 2018

Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine.

Brown SA et al.

Journal of Personalized Medicine, 2018

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Zhou Y et al.

Clinical Pharmacology and Therapeutics, 2017

Pharmacogenetics of CYP2C19 genetic polymorphism on clopidogrel response in patients with ischemic stroke from Saudi Arabia.

Alhazzani AA et al.

Neurosciences (riyadh, Saudi Arabia), 2017

Comparison of CYP2C9, CYP2C19, CYP2D6, ABCB1, and SLCO1B1 gene-polymorphism frequency in Russian and Nanai populations.

Sychev DA et al.

Pharmacogenomics and Personalized Medicine, 2017

Harnessing Knowledge on Very Important Pharmacogenes CYP2C9 and CYP2C19 Variation for Precision Medicine in Resource-Limited Global Conflict Zones.

Barlas İÖ et al.

Omics : a Journal of Integrative Biology, 2016

A prospective observational study of CYP2C19 polymorphisms and voriconazole plasma level in adult Thai patients with invasive aspergillosis.

Chuwongwattana S et al.

Drug Metabolism and Pharmacokinetics, 2016

Pharmacogenetics of healthy volunteers in Puerto Rico.

Claudio-Campos K et al.

Drug Metabolism and Personalized Therapy, 2015

Characterization of CYP1A2, CYP2C19, CYP3A4 and CYP3A5 polymorphisms in South Brazilians.

Kohlrausch FB et al.

Molecular Biology Reports, 2014

Clonal architectures and driver mutations in metastatic melanomas.

Ding L et al.

Plos One, 2014

25393105 (PubMed )
Supplement: pone.0111153.s002.zip › File_S2 › Table_S11.xls › Supp_Table_11

Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients.

Seong SJ et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2013

CYP2C19 polymorphisms in the Thai population and the clinical response to clopidogrel in patients with atherothrombotic-risk factors.

Sukasem C et al.

Pharmacogenomics and Personalized Medicine, 2013

Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients.

Seredina TA et al.

Bmc Medical Genetics, 2012

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Pharmacogenomics of clopidogrel: evidence and perspectives.

Yin T et al.

Thrombosis Research, 2011

Novel drug metabolism indices for pharmacogenetic functional status based on combinatory genotyping of CYP2C9, CYP2C19 and CYP2D6 genes.

Villagra D et al.

Biomarkers in Medicine, 2011

CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study.

Harmsze AM et al.

European Heart Journal, 2010

[Genetic polymorphism of CYP-450 in drug development].

Nonen S et al.

Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica, 2009

Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam.

Veiga MI et al.

European Journal of Clinical Pharmacology, 2009

Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.

Matimba A et al.

Human Genomics, 2009

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

Zandvliet AS et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2007

Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips.

Nakamoto K et al.

Pharmacogenetics and Genomics, 2007

Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese.

Maekawa K et al.

Pharmacogenetics and Genomics, 2006

The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives.

Sim SC et al.

Methods in Molecular Biology (clifton, N.j.), 2006

Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis.

Takada K et al.

Arthritis and Rheumatism, 2004

Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population.

Gaikovitch EA et al.

European Journal of Clinical Pharmacology, 2003

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily.

Goldstein JA

British Journal of Clinical Pharmacology, 2001

The Human Cytochrome P450 Allele Nomenclature Committee Web Site : Submission Criteria, Procedures, and Objectives.

Sim SC et al.

Methods in Molecular Biology (clifton, N.j.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."