Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.I331V
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CYP2C9

NM_000771.4:p.I331V

Associated Papers

Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism.

Yuan LJ et al.

Toxicology and Applied Pharmacology, 2023

Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro.

Lan T et al.

Journal of Psychopharmacology (oxford, England), 2021

SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.

Zhang L et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Effects of CYP2C19 variants on methadone metabolism in vitro.

Lan T et al.

Drug Testing and Analysis, 2017

Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro.

Fang P et al.

Pharmacology, 2017

Presence of a single nucleotide polymorphism (RS3758581) in a boy with DRESS syndrome.

Anil H et al.

Central-european Journal of Immunology, 2017

Advances in molecular modeling of human cytochrome P450 polymorphism.

Martiny VY et al.

Journal of Molecular Biology, 2013

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese.

Maekawa K et al.

Pharmacogenetics and Genomics, 2006

The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population.

Liou YH et al.

Journal of Human Genetics, 2006

Amino acid residues affecting the activities of human cytochrome P450 2C9 and 2C19.

Niwa T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2002

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily.

Goldstein JA

British Journal of Clinical Pharmacology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."