Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.P337T
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CYP2C9

NM_000771.4:p.P337T

Associated Papers

Enzymatic activity of 38 CYP2C9 genotypes on ibuprofen.

Yuan LJ et al.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 2023

The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

Zhou Y et al.

The Pharmacogenomics Journal, 2022

36068297 (PubMed )
Supplement: 41397_2022_288_MOESM4_ESM.xlsx › Sheet1

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Clinical significance of the series of CYP2C9*non3 variants, an unignorable predictor of warfarin sensitivity in Chinese population.

Wang D et al.

Frontiers in Cardiovascular Medicine, 2022

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population.

Zhao FL et al.

Frontiers in Pharmacology, 2022

Comparison of CYP2C9 Activity in Ethiopian and Non-Ethiopian Jews Using Phenytoin as a Probe.

Abu Ghosh Z et al.

Frontiers in Pharmacology, 2020

Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism.

Tang PF et al.

Drug Design, Development and Therapy, 2020

SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.

Mei Z et al.

Bmc Cancer, 2018

29703253 (PubMed )
Supplement: 12885_2018_4298_MOESM2_ESM.xlsx › Sheet1

Function of 38 variants CYP2C9 polymorphism on ketamine metabolism in vitro.

Zheng X et al.

Journal of Pharmacological Sciences, 2017

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.

Isvoran A et al.

Drug Discovery Today, 2017

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

Hiratsuka M

Biological & Pharmaceutical Bulletin, 2016

Effects of cytochrome P450 2C9 polymorphism on bosentan metabolism.

Chen M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2014

Characterization of a novel CYP2C9 mutation (1009C>A) detected in a warfarin-sensitive patient.

Luo SB et al.

Journal of Pharmacological Sciences, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."