Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.L362I
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CYP2C9

NM_000771.4:p.L362I

Associated Papers

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.

Lewis DF et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 1998

Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole activity.

Ibeanu GC et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."