Varaico: Literature-Extracted Genetic Variants

Gene:CYP2C9
Variant:p.D397A
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CYP2C9

NM_000771.4:p.D397A

Associated Papers

A New Cloud-Native Tool for Pharmacogenetic Analysis.

Yuan DY et al.

Genes, 2024

38540411 (PubMed )
Supplement: genes-15-00352-s001.zip › Pgxtools__a_new_cloud-native_tool_for_Pharmacogenetic_analysis-Supplemental-1-revised.pdf

Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach.

Avsar O

Nucleosides, Nucleotides & Nucleic Acids, 2024

CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project.

Gaedigk A et al.

The Journal of Molecular Diagnostics : Jmd, 2022

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

Pharmacogenetic determinants of warfarin in the Indian population.

Naushad SM et al.

Pharmacological Reports : Pr, 2021

PharmVar GeneFocus: CYP2C9.

Sangkuhl K et al.

Clinical Pharmacology and Therapeutics, 2021

Functional characterization of the defective CYP2C9 variant CYP2C9*18.

Liu J et al.

Pharmacology Research & Perspectives, 2021

Feasibility of Integrating Panel-Based Pharmacogenomics Testing for Chemotherapy and Supportive Care in Patients With Colorectal Cancer.

Kasi PM et al.

Technology in Cancer Research & Treatment, 2019

31533552 (PubMed )
Supplement: OneOme_sample_comprehensive_report.pdf

Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9.

Maekawa K et al.

Biochemistry, 2017

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

Hiratsuka M

Biological & Pharmaceutical Bulletin, 2016

Functional characterization of 32 CYP2C9 allelic variants.

Niinuma Y et al.

The Pharmacogenomics Journal, 2014

Advances in molecular modeling of human cytochrome P450 polymorphism.

Martiny VY et al.

Journal of Molecular Biology, 2013

Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.

Lee IS et al.

Archives of Pharmacal Research, 2011

Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

Zhou SF et al.

Toxicology, 2010

Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

Agúndez JA et al.

Expert Opinion on Drug Metabolism & Toxicology, 2009

Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese.

Maekawa K et al.

Pharmacogenetics and Genomics, 2006

Contribution of CYP2C9 to variability in vitamin K antagonist metabolism.

Daly AK et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.

DeLozier TC et al.

The Journal of Pharmacology and Experimental Therapeutics, 2005

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.

Zhao F et al.

Clinical Pharmacology and Therapeutics, 2004

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