Associated Papers
Natural Polymorphic Variants in the CYP450 Superfamily: A Review of Potential Structural Mechanisms and Functional Consequences.
Prost R et al.
International Journal of Molecular Sciences, 2025
Enzymatic activity of 38 CYP2C9 genotypes on ibuprofen.
Yuan LJ et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 2023
Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.
Lanillos J et al.
Npj Genomic Medicine, 2022
Clinical significance of the series of CYP2C9*non3 variants, an unignorable predictor of warfarin sensitivity in Chinese population.
Wang D et al.
Frontiers in Cardiovascular Medicine, 2022
Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population.
Zhao FL et al.
Frontiers in Pharmacology, 2022
Analysis of protein missense alterations by combining sequence- and structure-based methods.
Gyulkhandanyan A et al.
Molecular Genetics & Genomic Medicine, 2020
Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism.
Tang PF et al.
Drug Design, Development and Therapy, 2020
Function of 38 variants CYP2C9 polymorphism on ketamine metabolism in vitro.
Zheng X et al.
Journal of Pharmacological Sciences, 2017
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites.
Long T et al.
Nature Genetics, 2017
Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.
Isvoran A et al.
Drug Discovery Today, 2017
Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.
Hiratsuka M
Biological & Pharmaceutical Bulletin, 2016
Identification and Functional Assessment of a New CYP2C9 Allelic Variant CYP2C9*59.
Dai DP et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2015
Effects of cytochrome P450 2C9 polymorphism on bosentan metabolism.
Chen M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2014
[Identification of a novel CYP2C9 gene mutation (1400T>C) and assessment of its enzymatic activity in vitro].
Dai DP et al.
Zhonghua Yi Xue Za Zhi, 2013